Phosphoribosylanthranilate isomerase is also found in various forms of fungi such as " Kluyveromyces lactis " ( yeast ), " Saccharomyces cerevisiae " ( yeast ), and " Ashbya gossypii ".
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Demain and his team in the Department of Fermentation Microbiology also studied the overproduction of l-glutamic acid ( GA ) by Corynebacterium glutamicum, since Merck was selling monosodium glutamate ( MSG ) at the time . In addition, the team managed to boost production yields of vitamin B12 . Around 1966, Demain later said, Max Tishler, the President of MSDRL, gave me the responsibility to develop a microbiological riboflavin ( vitamin B2 ) process . . . . We chose Ashbya gossypii as our organism because it was already known to make 5g / liter.
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