Bacterial antigens stimulate white blood cells to release MIF into the blood stream.
2.
Odontoblasts, ( the cells that form dentin ) have cellular processes that extend into dentinal tubules and are the first to encounter the caries bacterial antigens.
3.
In the same way bacterial antigens can cause inflammatory response, HLA antigens from the donor of the organ caused an inflammatory response when placed in a recipient.
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CD4 + T cells are the major effectors of heart tissue autoimmune reactions in RHD . Normally, T cell activation is triggered by the presentation of bacterial antigens.
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Oral tolerance may depend on the same mechanisms of peripheral tolerance that limit inflammation to bacterial antigens in the microbiome, since both involve the gut-associated lymphoid tissue.
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The " molecular mimicry hypothesis " is similar, however it suggests that cross reactivity between some bacterial antigens and self peptide can break tolerance and lead to autoimmunity.
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Synovial fluid cultures are negative, suggesting that reactive arthritis is caused either by an autoimmune response involving cross-reactivity of bacterial antigens with joint tissues or by bacterial antigens that have somehow become deposited in the joints.
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Synovial fluid cultures are negative, suggesting that reactive arthritis is caused either by an autoimmune response involving cross-reactivity of bacterial antigens with joint tissues or by bacterial antigens that have somehow become deposited in the joints.
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For example, proteomics is highly useful in identification of candidate biomarkers ( proteins in body fluids that are of value for diagnosis ), identification of the bacterial antigens that are targeted by the immune response, and identification of possible immunohistochemistry markers of infectious or neoplastic diseases.
10.
In addition, chronic arthritis secondary to " S . flexneri " infection, called reactive arthritis, may be caused by a bacterial antigen; the occurrence of this syndrome is strongly linked to HLA-B27 genotype, but the immunologic basis of this reaction is not understood.
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