1. The equilibrium of the reaction favors the formation of barbituric acid . 2. Barbiturase is very specific to barbituric acid and will not react with derivatives. 3. Urea, malonate, and cyanuric acid inhibit the hydrolysis of barbituric acid . 4. In addition, barbituric acid inhibits multiple enzymes that are involved in de novo pyrimidine synthesis. 5. Barbiturates are derivatives of barbituric acid . 6. It is a common reagent for organic synthesis used, for example, as a precursor for barbituric acid . 7. Which is a multicomponent reaction of N, N'- dimethyl-barbituric acid , benzaldehyde and ethyl vinyl ether. 8. In 1903, he published observations that barbital ( then known as diethyl-barbituric acid ) has sedative properties in humans. 9. In 1912, Bayer introduced another barbituric acid derivative, phenobarbital, under the trade name Luminal, as a sedative-hypnotic. 10. The species is prepared by addition of ammonia to o-phthalonitrile to give the diiminoisoindoline, which in turn condenses with barbituric acid .
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