*Cyanoacetic acid from cathodic reduction of carbon dioxide and anodic oxidation of acetonitrile.
2.
Cyanoacetic acid is used to do cyanoacetylation, first convenient method described by J . Sl�tt.
3.
Cyanoacetic acid is a versatile intermediate in the preparation of chemicals . it is a precursor to synthetic caffeine via the intermediacy of theophylline.
4.
A Reformatsky reaction with zinc amalgam and bromoacetic ester leads to carbinol ( "'5 "'), which is then dehydrated with tosic acid to indene "'6 "'. { Alternatively ths step can be performed in a Knoevenagel condensation with cyanoacetic acid, which is then further decarboxylated .}
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