null allele sentence in Hindi
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- HMG-CoA reductase null alleles or mutations, simvastatin therapy may actually be toxic.
- These 4 microsatellite loci were all prone to null alleles.
- However, with the presence of these null alleles, the results may have been slightly biased.
- Thus we may consider the allele for the O blood type as a null allele.
- DRB1 * 0710N is a null allele.
- Alternatively, the technique can be used to create null alleles so that the gene is not functional.
- However, the frequency of heterozygous null alleles is much higher than expected, indicating a heterozygous advantage for TPI null alleles.
- However, the frequency of heterozygous null alleles is much higher than expected, indicating a heterozygous advantage for TPI null alleles.
- In fact, the mutants for these genes do not show the usual phenotype, that of the null alleles of A genes.
- Other mutations, which inactivate the enzyme ( = null alleles ) are lethal when inherited heterozygotes ( one defective and one normal copy ).
- Bearers of null alleles would be expected to be poor metabolizers of several drugs which are CYP2C19 * 2 or CYP2C19 * 3 substrates.
- If a mutation occurs in the annealing site, then the marker can no longer be used and the allele is turned into a null allele.
- A null allele is a gene variant that lacks the gene's normal function because it either is not expressed, or the expressed protein is inactive.
- Another definition of "'null allele "'concerning molecular markers, refers to such a marker in the case it can no longer be detected because of a mutation.
- One example of a null allele is the'O'blood type allele in the human A, B and O homozygous OO individuals as the lack of any blood antigen.
- A genetic null allele can be a protein and RNA null, but can also express normal levels of a gene product that is non-functional due to mutation.
- They found that if you have two null alleles ( two copies of a gene variant that doesn't function fully ) then you have an increased likelihood of having red hair.
- Probably through a Mexican grandmother, he carries the Duffy null allele, he said, a gene variant that protects against malaria and is very common in sub-Saharan Africans but rare among others.
- As one example, the Duffy Null allele ( FY * 0 ) has a frequency of almost 100 % of Sub-Saharan Africans, but occurs very infrequently in populations outside of this region.
- So at N1, the first backcross, you will select mice that have one allele that is B6 and the other has to be the null allele, which is on a 129 background.
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