1. A DNA polymerase extends the primed segments, forming Okazaki fragments . 2. A series of experiments eventually lead to the discovery of Okazaki fragments . 3. In contrast, lagging strand synthesis is accomplished in short Okazaki fragments . 4. Severe defects of Okazaki fragment maturation may halt DNA replication and induce cell death. 5. Each Okazaki fragment requires a separate RNA primer. 6. This constant initiation of Okazaki fragment synthesis requires repeated PCNA loading for efficient DNA replication. 7. This enzyme makes discontinuous segments ( called Okazaki fragments ) before DNA ligase joins them together . ]] 8. These new stretches of DNA are " called Okazaki fragments and each one requires its own RNA primer. 9. The interaction between DnaG and DnaB is necessary to control the longitude of Okazaki fragments on the lagging strand. 10. Based on the dangers associated with a failure in the DNA process, Okazaki fragments maintain our evolutionary development.