1. CD34 and Myf5 markers specifically define the majority of quiescent satellite cells . 2. Activated satellite cells initially proliferate as skeletal myoblasts before undergoing myogenic differentiation. 3. Satellite cells are described as quiescent myoblasts and neighbor muscle fiber sarcolemma.4. Finally, the muscle fibers that form later arise from satellite cells . 5. In response to mechanical strain, satellite cells become " activated ". 6. Satellite cell activation has also been demonstrated on an ultrastructural level following exercise.7. MGF expression results in activation of satellite cells and hypertrophy. 8. HGF testing is also used to identify active satellite cells . 9. Satellite cells are crucial for skeletal muscle adaptation to exercise.10. In addition, satellite cells have the capability to also differentiate into bone or fat.
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