Evaluating steady-state damages in specific tissues of the rat, Nakamura and Swenberg indicated that the number of abasic sites varied from about 50, 000 per cell in liver, kidney and lung to about 200, 000 per cell in the brain.
12.
Thus, it was proposed that base excision repair of DNA damage such as a uracil base, an abasic site, or a single-strand nick is sufficient to initiate meiotic crossover recombination in " S . pombe " and " C . elegans ".
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