A study in mice by Krieg et al . found that a mutation of the pump s ? subunit led to achlorhydria which resulted problems with iron absorption, leading to iron deficiency and anemia.
12.
If there is an insufficient production of hydrochloric acid in the stomach, hypochlorhydria / achlorhydria can occur ( often due to chronic H . pylori infections or long-term proton pump inhibitor therapy ).
13.
Achlorhydria associated with " Helicobacter pylori " infection may respond to H pylori eradication therapy, although resumption of gastric acid secretion may only be partial and it may not always reverse the condition completely.
14.
There are conflicting indications of abnormal lysosomal pH in MLIV . It is not yet clear why these abnormalities will cause incomplete development of the brain, achlorhydria, and failure in the maintenance of retinal tissue.
15.
This complex, referred to as the watery diarrhea, hypokalemia, and achlorhydria syndrome ( VIPoma ), has been ascribed to vasoactive intestinal polypeptide, although other intestinal hormones or secretagogues ( including prostaglandins ) may contribute.
16.
Plasma gastrin concentration is elevated in virtually all individuals with mucolipidosis type IV ( mean 1507 pg / mL; range 400-4100 pg / mL ) ( normal 0-200 pg / mL ) secondary to a constitutive achlorhydria.
17.
For example, after failed attempts to infect piglets in 1984, Barry Marshall drank a petri dish of the Helicobacter pylori from a patient, and soon developed gastritis, achlorhydria, stomach discomfort, nausea, vomiting, and halitosis.
18.
He was surprised when, only three days later, he developed vague nausea and halitosis ( due to the achlorhydria, there was no acid to kill bacteria in the stomach, and their waste products manifested as bad breath ), noticed only by his mother.
19.
The Heidelberg Diagnostic test is used to diagnose Hypochlorhydria ( reduced acid production ), Hyperchlorhydria ( excessive acid production ), Achlorhydria ( no acid production ), Pyloric Insufficiency, Heavy Stomach Mucus ( from infection or ulceration ), Acute and Sub-acute Gastritis.
20.
The massive amounts of VIP in turn cause profound and chronic watery diarrhea and resultant dehydration, hypokalemia, achlorhydria ( hence " WDHA-syndrome ", or " pancreatic cholera syndrome " ), acidosis, vasodilation ( flushing and hypotension ), hypercalcemia and hyperglycemia.
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