The MIT scientists grew crystals of a stretch of Z-DNA tightly bound to the editing enzyme, called RNA adenosine deaminase.
12.
This has already been investigated in a select few proteins such as adenosine deaminase, which acts on RNA ( ADAR ).
13.
In 2002 this work led to the publication of the first successful gene therapy treatment for adenosine deaminase-deficiency ( SCID ).
14.
Tuberculosis pleural effusions can now be diagnosed accurately by increased levels of pleural fluid adenosine deaminase, above 40 U per liter.
15.
PNPase, together with adenosine deaminase ( ADA ), serves a key role in purine catabolism, referred to as the salvage pathway.
16.
Adenosine Deaminase Acting on RNA is one of the most common forms of RNA editing, and has both selective and non-selective activity.
17.
In 2002 this work led to the publication of the first successful gene therapy treatment for adenosine deaminase deficiency ( SCID ).
18.
This family consists of the N-terminus and thus the z-alpha domain of double-stranded RNA-specific adenosine deaminase ( ADAR ), an RNA-editing enzyme.
19.
RNA-editing deaminase-2 ( RED2, or ADARB2 ) is a member of the double-stranded RNA ( dsRNA ) adenosine deaminase family of RNA-editing enzymes.
20.
Double-stranded RNA-specific adenosine deaminase ( EC ) converts multiple adenosines to inosines and creates I / U mismatched base pairs in double-helical RNA domain.
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