11. This should not be confused with agranulocytosis . 12. Adverse effects may include allergic reactions, vitamin B insufficiency, agranulocytosis and aplastic anemia. 13. Colloidal silver is also toxic to the bone marrow and may be associated with agranulocytosis . 14. Metiamide was an effective agent; however, it was associated with unacceptable nephrotoxicity and agranulocytosis . 15. Rarely, albendazole has been reported to cause marrow suppression, agranulocytosis , or aplastic anemia. 16. One possible side effect is agranulocytosis , a decrease of white blood cells in the blood. 17. Due to the risk of agranulocytosis its use as a biochemical reactions producing peroxides or phenols. 18. The study recommends carbamazepine to not be used concurrently with clozapine due to increased risk of agranulocytosis . 19. Agranulocytosis occurs rarely when dapsone is used alone but more frequently in combination regimens for malaria prophylaxis.20. Metiamide was an effective agent; it was associated, however, with unacceptable nephrotoxicity and agranulocytosis .