11. It includes methods found in statistics packages like regression analysis, analysis of variance and cluster analysis. 12. Lander and Botstein developed interval mapping, which overcomes the three disadvantages of analysis of variance at marker loci. 13. Repeated measures analysis of variance ( rANOVA ) is a commonly used statistical approach to repeated measure designs. 14. In its use of ranks it is similar to the Kruskal Wallis one-way analysis of variance by ranks. 15. As with other analysis of variance tests, the rANOVA makes use of an F statistic to determine significance. 16. It is the distribution of the test statistic in analysis of variance problems when the null hypothesis is false. 17. If the summed responses fulfill these assumptions, parametric statistical tests such as the analysis of variance can be applied. 18. The analysis of variance , the most common test used in hypothesis testing, assumes that the data is normally distributed. 19. In the analysis of variance ( ANOVA ), alternative tests include Levene's test, Bartlett's test, and the Brown Forsythe test. 20. Analysis of variance became widely known after being included in Fisher's 1925 book " Statistical Methods for Research Workers ".