In humans, anion exchangers fall under the solute carrier family 4 ( SLC4 ) family, which is composed of 10 paralogous members ( SLC4A1-5; SLC4A7-11 ).
12.
Examples of functional groups of strong ion exchange resins are quaternary ammonium ( Q ), which is an anion exchanger, and sulfonic acid ( S ), which is a cation exchanger.
13.
Cellulose, dextran, agarose and other insoluble complexes are unaffected because they compose inert matrices, hence why are they so often derivatized with strong and weak cation and anion exchangers in chromatography.
14.
When the stationary phase features positive groups which attracts anions, it is called an anion exchanger; when there are negative groups on the stationary phase, cations are attracted and it is a cation exchanger.
15.
The topology of the well-characterized human Anion Exchanger 1 ( AE1 ) conforms to a UraA-like topology of 14 TMSs ( 12 ?-helical TMSs and 2 mixed coil / helical TMSs ).
16.
In addition to the Na +-independent anion exchangers ( AE1-3 ) and the Na + : HCO cotransporters ( NBCs ) ( which may be either electroneutral or electrogenic ), a Na +-driven HCO / Cl " exchanger ( NCBE ) has been sequenced and characterized.
17.
The most recent families added include the PAAP ( Putative Amino Acid Permease ), LIVCS ( Branched Chain Amino Acid : Cation Symporter ), NRAMP ( Natural Resistance-Associated Macrophage Protein ), CstA ( Carbon starvation A protein ), KUP ( Kz Uptake Permease ), BenE ( Benzoate : Hz Virginia Symporter ), and AE ( Anion Exchanger ).
18.
Aldolase has also been implicated in many " moonlighting " or non-catalytic functions, based upon its binding affinity for multiple other proteins including F-actin, ?-tubulin, light chain dynein, WASP, Band 3 anion exchanger, phospholipase D ( PLD2 ), glucose transporter GLUT4, inositol trisphosphate, V-ATPase and ARNO ( a guanine nucleotide exchange factor of ARF6 ).
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