Growth hormone is made in the anterior pituitary gland, is released into the blood stream, and then stimulates the liver to produce IGF-1.
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This shows that the anterior pituitary gland is involved in behavioral functions as well as being part of a larger pathway for stress responses.
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Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.
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:; Stress : Operating through the hypothalamic-pituitary-adrenal axis ( HPA ), the anterior pituitary gland has a large role in the neuroendocrine system s stress response.
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Delta cells which produce somatostatin which is a growth hormone inhibiting hormone and has important function in the regulation of hormone production from the anterior pituitary gland.
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Prolactin is a peptide hormone produced by the anterior pituitary gland that is primarily associated with lactation and plays a vital role in breast development during pregnancy.
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FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland, and regulates the development, growth, pubertal maturation, and reproductive processes of the body.
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Production of T 3 and its prohormone thyroxine ( T 4 ) is activated by thyroid-stimulating hormone ( TSH ), which is released from the anterior pituitary gland.
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ACTH is a hormone produced in the anterior pituitary gland that stimulates the adrenal glands to release cortisol, dehydroepiandrosterone ( DHEA ), dehydroepiandrosterone sulfate ( DHEA-S ), and aldosterone.
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Thyroid hormone exerts negative feedback control over the hypothalamus as well as anterior pituitary, thus controlling the release of both TRH from hypothalamus and TSH from anterior pituitary gland.
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