11. The c4 antisense RNA has two regions, called a'and b'( see diagram ), that are complementary to its targets. 12. One way antisense RNA can act is by binding to an mRNA, forming double-stranded RNA that is enzymatically degraded. 13. In both prokaryotes and eukaryotes, antisense RNA sequences are produced, but the functions of these RNAs are not entirely clear. 14. The antisense RNA , said Harley, was tested against HeLa, a laboratory culture of cancer cells that can be grown endlessly. 15. Northern blot and RACE analysis confirmed the transcription of this antisense RNA and estimated it to be 540 nucleotides long. 16. The antisense RNA , BACE1-AS is transcribed from the opposite strand to BACE1 and is upregulated in patients with Alzheimer's disease. 17. Recruitment of the small ribosomal subunit can indeed be modulated by mRNA secondary structure, antisense RNA binding, or protein binding. 18. Although the function of some cases have been described, such as the Zeb2 / Sip1 antisense RNA , no general function has been elucidated. 19. The identification of c4 antisense RNAs solved the mystery of the mechanism for regulation of the " ant " gene, which is an anti-repressor. 20. It has been shown that NCYM antisense RNA encodes for a protein that has originated de novo and is specific to human and chimpanzee.
