Manufacture of oral chloramphenicol in the U . S . stopped in 1991, because the vast majority of chloramphenicol-associated cases of aplastic anaemia are associated with the oral preparation.
12.
Serious side effects include agranulocytosis, aplastic anaemia, hypersensitivity reactions ( like anaphylaxis and bronchospasm ), toxic epidermal necrolysis and it may provoke acute attacks of porphyria, as it is chemically related to the sulfonamides.
13.
Mutations involving the FANCA gene are associated with many somatic and congenital defects, primarily involving phenotypic variations of Fanconi anaemia, aplastic anaemia, and forms of cancer such as squamous cell carcinoma and acute myeloid leukaemia.
14.
It is not known whether monitoring the blood counts of patients can prevent the development of aplastic anaemia, but patients are recommended to have a baseline blood count with a repeat blood count every few days while on treatment.
15.
Fanconi anaemia is an inherited autosomal recessive disorder, the main features of which are aplastic anaemia in childhood, multiple congenital abnormalities, susceptibility to leukemia and other cancers, and cellular hypersensitivity to interstrand DNA cross-linking agents.
16.
The disease / virus has many names including chicken anaemia, blue wing disease, anaemia dermatitis syndrome, chicken / avian infectious anaemia, haemorrhagic aplastic anaemia syndrome, infectious chicken anaemia, chicken infectious anaemia virus and chicken anaemia agent.
17.
The concern is that racehorses are often treated with drugs like the anti-inflamatory phenylbutazone; doing this renders the horse's meat unfit for human consumption ( phenylbutazone causes aplastic anaemia, and may be carcinogenic, in humans ).
18.
The use of blood stem cells has emerged as a potentially curative option for the treatment of several diseases, including blood cancers ( such as leukemia and lymphoma ), and severe anaemia ( such as myelodysplastic syndrome, thalassemia major and severe aplastic anaemia ).
19.
In 1982, Dr . Fakhri designed an electric stimulator that could be used without pain or discomfort to the patient as an alternative to ECT . He used it for the first time in the treatment of resistant skin burns, exophthalmos, psoriasis and aplastic anaemia.
20.
There have been scattered reports of various problems when the oral form is used, including problems caused by myelosuppression ( leukopenia, neutropenia, agranulocytosis, aplastic anaemia, and thrombocytopenia, as well as hair loss, peripheral neuropathy, pancreatitis, liver problems, myocarditis and pericarditis, allergic and fibrotic lung reactions, lupus erythematosus-like reactions and rash ( including urticaria ), drug fever, interstitial nephritis and nephrotic syndrome, usually reversible on withdrawal.
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