11. The method then is an enantioselective asymmetric synthesis reaction. 12. This method of asymmetric synthesis is economically most desirable. 13. Asymmetric induction is a key element in asymmetric synthesis . 14. Homochirality may also result from spontaneous absolute asymmetric synthesis . 15. Enantiomeric excess is used as one of the indicators of the success of an asymmetric synthesis . 16. The reaction is also optimized for asymmetric synthesis . 17. In the Shiina esterification performed under basic conditions, asymmetric synthesis is realized using chiral nucleophilic catalysts. 18. Applications in asymmetric synthesis have been reported. 19. Related bidentate phosphine-containing ligands derived from other chiral diamines have also been developed for applications in asymmetric synthesis . 20. A similar reaction by asymmetric synthesis protected cysteine and potassium tert-butoxide afforded a cyclohexene with 95 % enantiomeric excess:
