11. The formation of the trans isomer would have indicated that the intermediate carbanion was unstable. 12. Stabilization of the resultant carbanion is provided by the S ( O ) R group. 13. She also researched carbanion reactivity, with emphasis on reactivity and structure of ion pairs. 14. Styrene reacts in toluene with sodium to 1, 3-diphenylpropane through the intermediate carbanion : 15. The initial stereochemistry of the reaction sequence is established in the step where the carbanion attacks the carbonyl. 16. Therefore, due to the Arg219, the PLP-stabilized carbanion intermediate is less likely to form. 17. Many carbanion synthons, as drawn, present stability issues that render the molecule s existence in reality impossible. 18. One further relevant point is that the first organic correlation diagrams were in a 1961 publication on carbanion rearrangements. 19. The C2 of this ring is capable of acting as an acid by donating its proton and forming a carbanion . 20. This unique combination of contacts and conformations of TPP leads to formation of the reactive C2-carbanion , eventually.
