11. A nonfunctioning centriole lies adjacent to the kinetosome. 12. These complexes are then anchored at the centriole to begin formation of the centrosome. 13. They undergo closed mitosis without centrioles , and typically have mitochondria with flat cristae. 14. The environment suitable for procentriole formation is provided by the base of each centriole . 15. Centrioles may also be associated in the formation of a spindle during nuclear division.16. Three Cdk2 substrates have been proposed to be responsible for regulation of centriole duplication. 17. Centrosome disorientation refers to the loss of orthogonality between the mother and daughter centrioles . 18. Centrioles are present in the cells of most eukaryotes, for example those of animals.19. They further show that if the centrioles are not eliminated, those mothers are sterile. 20. Centrioles start duplicating when DNA replicates.
