Since it is known to be associated with metastasis and malignant transformation, Bmi-1 makes for a good marker of cancer and may hold prognostic or diagnostic value . and it is known for its association with chemoresistance to common chemotherapeutics.
12.
In colorectal cancer, ABCB5 was shown to act as a mediator of 5-FU patient chemoresistance, and had a further direct role in tumorigenesis shown by shRNA-mediated colorectal cancer cell-line ABCB5 knockdowns that impeded tumorigenesis in human-to-mouse xenografts.
13.
This indicates that MK caused the cells to initiate the survival pathway ( via PKB, mTOR, and Bad activation ) and inhibit the senescent or apoptotic pathway ( via inhibiting caspase-3 ) encouraging the chemoresistance seen in resistant cells and in the co-culture experiments.
14.
Hyperthermia has also been shown to help prevent or reverse " chemo-resistance . " Chemotherapy resistance sometimes develops over time as the tumors adapt and can overcome the toxicity of the chemo medication . " Overcoming chemoresistance has been extensively studied within the past, especially using CDDP-resistant cells.
15.
In regard to the potential benefit that drug-resistant cells can be recruited for effective therapy by combining chemotherapy with hyperthermia, it was important to show that chemoresistance against several anticancer drugs ( e . g . mitomycin C, anthracyclines, BCNU, melphalan ) including CDDP could be reversed at least partially by the addition of heat.
How to say chemoresistance in Hindi and what is the meaning of chemoresistance in Hindi? chemoresistance Hindi meaning, translation, pronunciation, synonyms and example sentences are provided by Hindlish.com.
