11. But glucosamine and chondroitin are not the only hot new areas in arthritis. 12. Glucosamine Chondroitin MSM, Ultra Rx-Joint Cream, Greaseless Penetrating Action. 13. Most studies of glucosamine and chondroitin were done several years ago in Europe. 14. The contaminant was later found to be a compound called oversulfated chondroitin sulfate. 15. Chondroitin and glucosamine are also used in veterinary medicine.16. Sulfation in these different positions confers specific biological activities to chondroitin GAG chains. 17. As part of aggrecan, chondroitin sulfate is a major component of cartilage. 18. Loss of chondroitin sulfate from the cartilage is a major cause of osteoarthritis. 19. Other supplements given to dogs are glucosamine and chondroitin . 20. One of the many inhibitory cues includes chondroitin sulfate proteoglycans ( CSPGs ).