The "'chorioallantoic membrane "' also called the chorioallantois or abbreviated to CAM is a vascular membrane found in eggs of some amniotes, such as birds and reptiles.
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Isaacs and Lindenmann were working with a system that involved the inhibition of the growth of live influenza virus in chicken embryo chorioallantoic membranes by heat-inactivated influenza virus.
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Definitive laboratory identification of variola virus involves growing the virus on chorioallantoic membrane ( part of a chicken embryo ) and examining the resulting pock lesions under defined temperature conditions.
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A 1995 study funded by the European Commission and British Home Office evaluated these among nine potential replacements, including the hens'egg chorioallantoic membrane ( HET-CAM ) assay and an epithelial model cultivated from human corneal cells, in comparison with Draize test data.
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