11. This gene encodes a coiled coil domain-containing protein. 12. Computation has been used to design proteins with unnatural folds, such as a right-handed coiled coil . 13. They are referred to as coiled coils unless they are proven to be important for protein function. 14. Furthermore, each coronin contains a unique divergent region between the WD domain and C-terminal coiled coil region. 15. Hook proteins are cytosolic coiled coil proteins that contain conserved C-terminal domains, which mediate binding to organelles. 16. This protein for this gene is also known as coiled coil domain containing 144A ( CCDC144A ) protein. 17. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. 18. At the top the braid unravels, and the loose ends fall down along the grooves of the coiled coil . 19. Although disfavored, a few " right-handed " coiled coils have also been observed in nature and in designed proteins. 20. The DUF1220 domains are important in neurogenesis, while the coiled coil domains involved with the binding of cell proliferation inhibitors.
