11. His post-doctoral training was with Han Mueller-Eberhart at the Scripps Clinic studying the complement system . 12. Mice without CRIg could not clear complement system -coated pathogens. 13. Sometimes antibodies are generated against tumor cells allowing for their destruction by the complement system . 14. Binding of antibodies to red blood cells activates the classical pathway of the complement system . 15. Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system . 16. Most of the proteins and glycoproteins that constitute the complement system are synthesized by hepatocytes. 17. Furthermore, IgY does not activate the complement system . 18. Although the number is an exception, it is a valid number in regular two's complement systems . 19. This function prevents the inappropriate activation of the complement system , which would cause uncontrolled systemic inflammation. 20. For example, the severity of a dysfunctional complement system can lead to fatal diseases and infections.