11. In a similar manner, propane and cyclopropane , butane and cyclobutane, etc. 12. An example of a unimolecular reaction, is the isomerization of cyclopropane to propene: 13. The simplest examples of angle strain are small cycloalkanes such as cyclopropane and cyclobutane. 14. This was used for the first synthesis of cyclopropane by August Freund in 1881. 15. The initially formed cyclopropane undergoes a ring expansion and subsequent elimination of hydrogen fluoride. 16. Thus, the two products are S-adenosylhomocysteine and phospholipid cyclopropane fatty acid. 17. It has a strained ring system with a cyclopentane ring fused to a cyclopropane ring. 18. Cyclopropane is an anaesthetic when inhaled.19. Singlet carbenes add stereospecifically to alkenes, and alkene stereochemistry is retained in the cyclopropane product. 20. In the 1980s it was found that dirhodium catalysts provide single cyclopropane isomers in high yields.
