The precursor of vitamin D 3, 7-dehydrocholesterol is produced in relatively large quantities . 7-Dehydrocholesterol reacts with UVA spectrum, but typically produce 4 % to 10 % of the total UV emissions as UVB ).
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The precursor of vitamin D 3, 7-dehydrocholesterol is produced in relatively large quantities . 7-Dehydrocholesterol reacts with UVA spectrum, but typically produce 4 % to 10 % of the total UV emissions as UVB ).
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Because the newly discovered substance was the fourth vitamin identified, it was called vitamin D . The 1928 Nobel Prize in Chemistry was awarded to Adolf Windaus, who discovered the steroid 7-dehydrocholesterol, the precursor of vitamin D.
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Within the epidermal layer of skin, 7-Dehydrocholesterol undergoes an electrocyclic reaction as a result of UVB radiation, resulting in the opening of the vitamin precursor B-ring through a sigmatropic rearrangement and therein finally isomerizes to form vitamin D 3.
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UVB radiation with a wavelength of 290 315 nanometers penetrates uncovered skin and converts cutaneous 7-dehydrocholesterol to UV intensity and vitamin D synthesis, Individuals with limited sun exposure need to include good sources of vitamin D in their diet or take a supplement.
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However, approximately 10 % may show normal cholesterol levels, and decreased concentrations of cholesterol are not solely indicative of SLOS . Increased levels of cholesterol precursors are also common in SLOS . In particular, elevated levels of 7-dehydrocholesterol are fairly specific to SLOS.
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