11. However, how sulfatide buildup causes demyelination and neural degeneration is still mostly unknown. 12. Once demyelination of the pons has begun, there is no cure or specific treatment. 13. Anti-MOG mediated demyelination was shown to behave similar to NMO in animal models, 14. Electromyographic studies and noninflammatory axonopathy without demyelination . 15. This demyelination is shown to cause mitochondrial dysfunction in axons, leading to their degeneration. 16. In these cases it is only possible to speak about tumefactive demyelination ( TD ). 17. Unexplained, uniform demyelination of white matter can indicate acute onset Grinker's myelinopathy. 18. Fibers were observed some of which showed a sign of primary ( segmental ) demyelination . 19. There is a combination of demyelination and axonal damage, and autonomic neurones are all affected. 20. This leads to cerebral inflammatory demyelination caused by the myelin destabilization that occurs in these patients.
