Dens invaginatus is a malformation of teeth most likely resulting from an infolding of the dental papilla during tooth development or invagination of all layers of the enamel organ in dental papillae.
12.
When the tissues of the developing tooth are seen under a microscope, different cellular aggregations can be identified, including structures known as the enamel organ, dental lamina, and dental papilla.
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The "'Hertwig epithelial root sheath "'( HERS ) or "'epithelial root sheath "'is a proliferation of differentiation of odontoblasts from the dental papilla.
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The tooth bud ( sometimes called the tooth germ ) is an aggregation of cells that eventually forms a tooth and is organized into three parts : the enamel organ, the dental papilla and the dental follicle.
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Thus with the formation of primary dentin, the cell moves pulpally, away from the basement membrane ( future dentinoenamel junction ) at the interface between the inner enamel epithelium and dental papilla, leaving behind the odontoblastic process within the pulp.
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During secretion after differentiation from the outer cells of the dental papilla, it is noted that it is polarized so its nucleus is aligned away from the newly formed dentin, with its Golgi complex and endoplasmic reticulum towards the dentin reflecting its unidirectional secretion.
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