11. Deuterated THF is rarely used as a solvent in NMR spectroscopy due to its expense.12. Deuterated DCM is not a common solvent used in NMR spectroscopy as it is reasonably expensive.13. If these peaks pose a problem, a deuterated version of DSS is available at much higher cost. 14. Compound II was treated with dimethoxyethane / D2O / triethylamine and was found to be completely deuterated upon recovery. 15. Specific exchangeable hydrogens in a non-deuterated protein may be imaged if it is exposed to heavy water. 16. One or both of the hydrogen atoms in water can be substituted with the deuterated version of hydrogen disulfide. 17. The deuterated compound was then treated with butyllithium in ether, with dimethoxyethane and 2N HCl regenerating the starting material. 18. The magnet is stabilized with an internal 2H lock so the use of deuterated solvents is recommended but not required. 19. CH 2 N 2 reacts with basic solutions of D 2 O to give the deuterated derivative CD 2 N 2. 20. At the same time Turin and coworkers reported that human volunteers were able to distinguish cyclopentadecanone from its fully deuterated analog.
