11. It is found in the endoplasmic reticulum and is highly conserved. 12. The conversion of zymosterol into cholesterol happens in the endoplasmic reticulum. 13. KKXX-like motifs are predicted endoplasmic reticulum membrane retention signals. 14. C5SD is located in both the endoplasmic reticulum and lipid particles. 15. The endoplasmic reticulum is the laundry room of the cell. 16. The rough endoplasmic reticulum is especially prominent in cells such as hepatocytes. 17. The major intracellular compartments are endoplasmic reticulum, Golgi apparatus and mitochondria. 18. The signal peptide is cleaved off in the endoplasmic reticulum. 19. It is known to bind to endoplasmic reticulum anchored human VAP proteins. 20. Endoplasmic reticulum degrades and mitochondria swell up and eventually disintegrate.