11. Fibrocystic lumps are fairly harmless, fluid-filled sacs that are enlarged and tender.12. Dear Dr . Smith : What is " Fibrocystic Disease " of the wrist? 13. They diagnosed it as fibrocystic disease. 14. Duct widening with associated periductal fibrosis is frequently included in the wastebasket definition of fibrocystic disease. 15. Adjemian has no family history of breast cancer but does have a personal medical history of fibrocystic disease. 16. Several variants of fibrocystic breast changes may be distinguished and these may have different causes and genetic predispostions. 17. He also showed that the drug Danazol was useful in the management of endometriosis and fibrocystic breast disease. 18. Women with fibrocystic changes may experience a persistent or intermittent breast aching or breast tenderness related to periodic swelling. 19. Fibrocystic breast disease is primarily diagnosed based on the symptoms, clinical breast exam and on a physical exam.20. He is remembered for his introduction of surgical techniques associated with subcutaneous mastectomy for treatment of fibrocystic breast disease.