11. Fluorescence microscopy and confocal microscopy are used to detect fluorescent signals with good intracellular detail.12. An example of fluorescence microscopy today is two-photon or multi-photon imaging. 13. Luminescent conjugated oligothiophenes can also be used to detect cellulose using fluorescence microscopy or spectrofluorometric methods. 14. Calcium concentration microdomains can be visualised with fluorescence microscopy by using aequorin as a reporter protein. 15. This relationship was confirmed in 1999 with co-capping experiments and with conventional fluorescence microscopy . 16. GUVs are large enough ( several tens of micrometres ) to study with traditional fluorescence microscopy . 17. PI is suitable for fluorescence microscopy , confocal laser scanning microscopy, flow cytometry, and fluorometry. 18. The rise of fluorescence microscopy drove the development of a major modern microscope design, the confocal microscope. 19. Monoclonal antibodies, specific to the virus, are also used for detection, as in fluorescence microscopy . 20. For fluorescence microscopy a smear of washed sperm cells are made, airdried, permealized and then stained.