11. Most of these individuals showed either a deletion or an insertion resulting in a frameshift mutation . 12. Frameshift mutations and the genetic code.13. A homozygous 1-bp deletion inducing a frameshift mutation in STAG3 causes premature ovarian failure. 14. This causes a problem because SOS1 introduces a frameshift mutation and creates a premature stop codon. 15. As stated previously, frameshift mutations are more likely to occur in a region of repeat sequence. 16. In a 2006 study in which 110 patients were tested, 28 suffered from this frameshift mutation . 17. This region on the open reading frame ORF contains a frameshift mutation leading to a premature stop codon. 18. They used frameshift mutations and a process called reversions, to add and delete various numbers of nucleotides. 19. There are 11 types of mutations that have been identified, but the most common being frameshift mutations . 20. Frameshift mutations are known to be a factor in colorectal cancer as well as other cancers with microsatellite instability.
