11. Leptin is known to interact with amylin, a hormone involved in gastric emptying and creating a feeling of fullness. 12. The presence of fat or soluble dietary fiber can slow the gastric emptying rate, thus lowering the glycemic response. 13. Recently, it has been reported that ICV nesfatin-1 produced a dose-dependent delay of gastric emptying . 14. Gastric emptying of clear fluids such as water or black coffee is only affected in highly progressed delayed gastric emptying.15. Gastric emptying of clear fluids such as water or black coffee is only affected in highly progressed delayed gastric emptying . 16. Difficulty in emptying the stomach ( delayed gastric emptying ) is common and can be a serious problem, involving hospitalization. 17. The Phase II trials did not detect an increase in gastric emptying among the population of diabetic gastroparesis patients above placebo. 18. Because many diabetics take oral medication for their diabetes, absorption of these medicines is greatly affected by the delayed gastric emptying . 19. Metoclopramide, a dopamine D 2 receptor antagonist, increases contractility and resting tone within the GI tract to improve gastric emptying . 20. They also slow the rate of absorption of nutrients into the blood stream by reducing gastric emptying and may directly reduce food intake.
