11. Each of those are linked to a specific Hox gene cluster . 12. This gene is part of a gene cluster on chromosome Xp11.23. 13. The next reactions are catalyzed by enzymes originating from the dnr gene cluster . 14. This gene is located at the chemokine receptor gene cluster region. 15. The complete biosynthetic gene cluster for bottromycin has been identified. 16. In the case where a gene cluster is duplicated, some genes may be lost. 17. The pneumocandin biosynthetic gene cluster was previously elucidated by a whole genome sequencing approach. 18. The protocadherin-beta gene cluster on chromosome 5 also shows evidence of possible positive selection. 19. Thirty-five of these ORFs are similar to those found in other glycopeptide gene clusters . 20. The standard nomenclature for thiopeptide biosynthetic proteins follows that of the thiomuracin gene cluster .