11. These desmoglein gene family members are located in a cluster on chromosome 18. 12. An approved nomenclature has been established for the five mammalian carboxylesterase gene families . 13. Capecchi has also pursued a systematic analysis of the mouse Hox gene family . 14. This intronless gene is a member of the frizzled gene family . 15. This gene encodes a transmembrane receptor of the patched gene family . 16. This gene encodes a member of the lysyl oxidase gene family . 17. This gene encodes one member of the sodium channel alpha subunit gene family . 18. This gene is a member of the melanoma-associated antigen gene family . 19. Expansion replaces lost gene copies and prevents gene families from becoming too small. 20. This gene belongs to the DAZ gene family required for germ cell development.