11. Gluten consists of a mixture of prolamins :'glutenin'and'gliadin '. 12. Working with gliadin , he identified ?-aminoglutaric acid or glutamic acid in 1866. 13. Gliadin can cross the intestinal epithelium.14. The major gluten proteins that are involved in coeliac disease are the ?-gliadin isoforms. 15. The best known storage protein in wheat is the prolamin gliadin , a component of gluten. 16. Glutenin and gliadin are functional proteins found in wheat bread that contribute to the structure of bread. 17. This, however, could interfere with the effects that gliadin has on the quality of dough. 18. DQ2.5 binds gliadin , but the binding is sensitive to deamidation caused by tissue transglutaminase. 19. While not truly innate, these activities allow gliadin to enter into areas where many lymphocytes patron. 20. In at least 1 % of coeliacs DQ2.2 confers adaptive immunity to gliadin permitting coeliac disease.
