11. Segmental hemangiomas are larger, appear to encompass a region of the body. 12. Discomfort may arise if the hemangioma is bulky and blocks a vital orifice. 13. In the involution phase, a hemangioma finally begins to diminish in size. 14. Congenital swellings are present since birth, such as a hemangioma or meningocele. 15. Glut1 has also been demonstrated as a powerful histochemical marker for hemangioma of infancy 16. Additionally, low birthweight infants have a 26 % chance of developing a hemangioma . 17. The most common symptom affecting the CNS is an intracranial hemangioma in the midbrain. 18. PHACE syndrome should be considered in infants with large plaque-type facial hemangiomas . 19. Kennedi takes an experimental drug and steroids are used to inhibit growth of the hemangiomas . 20. This marker has revolutionized the ability to distinguish between infantile hemangioma and other vascular anomalies.