TK is currently being investigated in patients suffering from acute leukemia in first or subsequent complete remission and at high risk of relapse or in patients with relapsed disease who are candidates for haploidentical transplantation of hemopoietic stem cells ( taken from a partially HLA-compatible family donor ).
12.
Hemopoietic stem cells were cultured ( see cell culture ) on a so-called semisolid matrix, which prevents cells from moving around, so that, if a single cell starts proliferating, all of the cells derived from it will remain clustered around the spot in the matrix where the first cell was originally located.
13.
Since a patient's bone marrow is virtually guaranteed not to survive a course of CBV, the receiving patient must receive a transplant ( allogeneic or autologous, depending on his or her condition ) of stem cells ( formerly referred to as a bone marrow transplant ) to replace the patient's own hemopoietic ( " blood-forming " ) stem cells.
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