The structure of the hinge regions ( region 6 in the diagram ) contributes to the unique biological properties of each of the four IgG classes.
12.
The human androgen receptor ( AR ) is a protein encoded by a gene located on the 5'portion of exon 4 encodes the hinge region.
13.
The outer surface of the scutes consists of the relatively rigid beta-keratin while the hinge region between the scutes contains only the more pliable alpha-keratin.
14.
Structurally, it is composed of three distinct regions : an N-terminal protein domain, a hinge region and a C-terminal cystein-rich domain.
15.
One of the characteristics of IgA 1 ( and IgD ) is the presence of an 18 amino acid-long " hinge region " between O-glycosylation ).
16.
The kinase domain usually consists of a bi-lobed structure, where the lobes are connected with a hinge region, adjacent to the very conserved ATP binding site.
17.
Historically, this autoinhibitory block was labelled as the CR1 region ( " Conserved Region 1 " ), the hinge region being named CR2, and the kinase domain CR3.
18.
Papain cleaves IgG above the hinge region containing the disulfide bonds that join the heavy chains, but below the site of the disulfide bond between the light chain and heavy chain.
19.
The hinge region of antithrombin in the Figure 5 complex could not be modelled due to its conformational flexibility, and amino acids P9-P14 are not seen in this structure.
20.
PIM 2 ( along with PIM1 ) has a unique binding pocket for ATP with a hinged region, making it an attractive target for potent small-molecule PIM kinase inhibitors.
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