11. The encoded protein forms a multiple-protein RNA editing holoenzyme with APOBEC1 complementation factor ( A1CF ). 12. Elp3 has the ability to acetylate all histone subunits and also shows involvement in the RNA polymerase II holoenzyme . 13. It should be noted that the above promoter sequences are recognized only by RNA polymerase holoenzyme containing sigma-70. 14. RNA polymerase holoenzyme complex consisting of core RNA polymerase and a sigma factor executes transcription of a DNA template strand. 15. It is also known that vitamin B12 can repress MetE gene expression, which is mediated by the MetH holoenzyme . 16. This is typical in many staphylococcal lysins as well as the streptococcal PlyC holoenzyme , which contains two catalytic domains. 17. It can be released upon E . coli " without the co-factor results in an inactive holoenzyme . 18. This protein has also been used in fluorescent sensing either simply as an apoenzyme or as an as a holoenzyme . 19. The complete holoenzyme therefore has 6 subunits : ?'?? I and ? II ?? ( ~ 450 kDa ). 20. An inactive enzyme without the cofactor is called an apoenzyme, while the complete enzyme with cofactor is called a holoenzyme .
