11. The physicians who treat some of the hypothalamic problems are endocrinologists and neurologists. 12. Metenolone enanthate can be suppressive of the hypothalamic -pituitary-gonadal axis. 13. They normalize the hypothalamic -pituitary-adrenal axis ( HPA axis ). 14. Numerous dysfunctions manifest as a result of hypothalamic disease. 15. Hypothalamic hamartomas are found in 33 % of patients with true precocious puberty.16. Hypothalamic and genetic obesity in experimental animals : An autonomic and endocrine hypothesis.17. Hypothalamic effects reach the cortex via a relay in the anterior thalamic nuclei ."18. Hypothalamic disease may therefore have implications for obesity.19. Adipsia can tend to result from lesions to hypothalamic regions involved in thirst regulation. 20. Patients also commonly develop severe aggression, he said, called " hypothalamic rage ."