11. Hypotonia is frequently seen in the 18p-population.12. Those afflicted suffer from seizures, global developmental delay, movement disorder and hypotonia . 13. Hypotonia may also occur in severe cases.14. Symptoms of CNM include severe hypotonia , hypoxia-requiring breathing assistance, and scaphocephaly. 15. Though there was hypotonia leading to paralysis. 16. Speech difficulties can result from hypotonia . 17. Rarely, hypotonia , dry mouth, urinary incontinence and nonspecific electrocardiographic ST segment changes occur. 18. However, rigidity is not fully controlled after successful thalamotomy, it is replaced by hypotonia . 19. As a consequence of complicated delivery due to nuchal cord, Melamed has generalized muscle hypotonia . 20. Two patients had hypotonia from birth.