The necessary quantity of urea for the formation of inclusion compounds varies from about 1 to 0.8 mole of urea per methyl-and methylene group in a carbon chain.
12.
This is the reason why cyclodextrins have attracted much interest in many fields, especially pharmaceutical applications : because inclusion compounds of cyclodextrins with hydrophobic molecules are able to penetrate body tissues, these can be used to release biologically active compounds under specific conditions.
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