An individual with the sickle cell trait shows incomplete dominance when the shape of the red blood cell is considered.
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Cases in which one allele is not completely dominant over another are called "'incomplete dominance " '.
13.
Co-dominance, where allelic products co-exist in the phenotype, is different from incomplete dominance, where the quantitative interaction of allele products produces an intermediate phenotype.
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A similar type of incomplete dominance is found in the four o'clock plant wherein pink color is produced when true-bred parents of white and red flowers are crossed.
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Given that this disease displays incomplete dominance, those who are homozygous for the mutated allele are at a heightened risk for the events detailed above versus those that are heterozygous for the mutation.
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Given that the trait of interest is either autosomal or sex-linked and follows by either complete dominance or incomplete dominance, a reciprocal cross following two generations will determine the mode of inheritance of the trait.
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Incomplete dominance ( also called " partial dominance " or " semi-dominance " ) occurs when the phenotype of the heterozygous phenotype is distinct from and often intermediate to the phenotypes of the homozygous phenotypes.
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Among the infinitely large number of potentially describable features, very few can be introduced as a purely Mendelian trait, because most of the phenotypic expression of the exophenotypic traits is the showpiece incomplete dominance, codominance and quantitative contributions from smaller or larger number of genes ( see : Polygenic inheritance, Oligogenic inheritance ).
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Another example occurs at the locus for the Beta-globin component of hemoglobin, where the three molecular phenotypes of " Hb A / Hb A ", " Hb A / Hb S ", and " Hb S / Hb S " are all distinguishable by protein electrophoresis . ( The medical condition produced by the heterozygous genotype is called " sickle-cell trait " and is a milder condition distinguishable from " sickle-cell anemia ", thus the alleles show " incomplete dominance " with respect to anemia, see above ).
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