This operon encodes the translation initiation factor IF-3 and ribosomal proteins L35 and L20.
12.
The PspA / IM30 family is a negative regulator of sigma54 transcription initiation factor in bacteria.
13.
EIF3 independently binds the 40S ribosomal subunit, multiple initiation factors, and cellular and viral mRNA.
14.
Eukaryotic initiation factor-2B ( EIF2B ) is a GTP exchange protein essential for protein synthesis.
15.
The other two subunits are related to Pol II initiation factors and have structural homologues in Pol III.
16.
The eIF4A translation initiation factor was the first DEAD box protein found to have a RNA dependent ATPase activity.
17.
These initiation factors must associate with the ribosome in stoichiometric proportions, while Rli1p is required in catalytic amounts.
18.
In mammals, eIF3 is the largest initiation factor, made up of 13 subunits ( a-m ).
19.
The encoded protein also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase.
20.
Such a mechanism is called translational recoding and its efficiency depends on the selenoprotein being synthesized and on translation initiation factors.
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