11. In others, it becomes more severe and chronic indicating a deficiency in innate immunity . 12. This may complicate the process of using experimental animals as models of human innate immunity . 13. TLR and hyaluronan play a role in innate immunity . 14. Olive leaf has also been suggested to support innate immunity through their interactions with macrophages. 15. This leads to NK cell activation and IFN-? production, which stimulates cells of innate immunity . 16. The TLR family plays a fundamental role in pathogen recognition and activation of innate immunity . 17. The TLR family plays an important role in pathogen recognition and activation of innate immunity . 18. NALP proteins are part of the innate immunity and detect conserved pathogen characteristics such as peptidoglycan. 19. Hence, trained innate immunity may provide a biological mechanism for the observed non-specific effects of vaccines. 20. One example is mannan-binding lectin, which is involved in innate immunity by facilitating phagocytosis of microorganisms.