11. In addition, swelling of cells and oedema due to inflammation cause mechanical obstruction of intrahepatic biliary tree. 12. Citrin is associated with type II citrullinemia and neonatal intrahepatic cholestasis caused by citrin deficiency ( NICCD ). 13. This protein is associated with progressive familial intrahepatic cholestasis type 1 as well as benign recurrent intrahepatic cholestasis. 14. This protein is associated with progressive familial intrahepatic cholestasis type 1 as well as benign recurrent intrahepatic cholestasis. 15. In liver disease ( such as hepatitis ), the intrahepatic urobilinogen cycle is inhibited also increasing urobilinogen levels. 16. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis. 17. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis. 18. Insertion of a transjugular intrahepatic portosystemic shunt ( TIPS ) has been shown to alleviate varices caused by portal hypertension. 19. Nitric oxide is an endogenous vasodilator and it regulates intrahepatic vascular tone ( it is produced from L-arginine ). 20. It should be noted that with the advent of transjugular intrahepatic portosystemic shunting ( TIPS ), portosystemic shunts are less performed.
