11. The protein shows sequence similarity to the protein disulfide-isomerase family. 12. Mutations in this gene are associated with triosephosphate isomerase deficiency. 13. Isomerase is defined by an equation that is not written very well.14. It is converted into 3-fumarylpyruvate by maleylpyruvate isomerase . 15. Tetrahydroxychalcone is then converted into naringenin using chalcone isomerase . 16. The PDIA3 protein is a thiol oxidoreductase that has protein disulfide isomerase activity. 17. IPP isomerase also requires a divalent cation to fold into its active conformation. 18. In vertebrates, RPE65 is the active retinol isomerase in the visual cycle. 19. Glucose-6-phosphate first binds to the active site of the isomerase . 20. This gene encodes a protein disulfide-isomerase .
