11. Otto & Marie Neurath fled from German invasion to England, where they established the Isotype Institute in 1942. 12. A second isotype is held at Herbarium Bogoriense ( BO ), the herbarium of the Bogor Botanical Gardens. 13. Ipilimumab, which is an IgG1 isotype , and tremelimumab ( from Pfizer ) which is an IgG2 isotype. 14. Ipilimumab, which is an IgG1 isotype, and tremelimumab ( from Pfizer ) which is an IgG2 isotype . 15. Of 40 patients receiving control, 25 had tumors with IgM isotype and 15 had tumors with IgG isotype. 16. Of 40 patients receiving control, 25 had tumors with IgM isotype and 15 had tumors with IgG isotype . 17. The constant region is identical in all antibodies of the same isotype , but differs in antibodies of different isotypes. 18. Anti-dsDNA antibodies can be present in normal individuals, however these antibodies are usually low avidity IgM isotype . 19. An isotype of the iris, was given to Museum Botanicum Hauniense of the University of Copenhagen in May 2010. 20. However, Matthew Jebb and Martin Cheek pointed out that this feature is not present in the isotype held in Singapore.